N1-FMOC-N4-BOC 2-PIPERAZINECARBOXYLIC ACID

N1-FMOC-N4-BOC 2-PIPERAZINECARBOXYLIC ACID - Names and Identifiers

Name	4-Boc-1-Fmoc-2-piperazinecarboxylic acid
Synonyms	4-Boc-1-Fmoc-2-piperazinecarboxylic acid 1-FMOC-4-BOC-PIPERAZINE-2-CARBOXYLIC ACID N1-FMOC-N4-BOC 2-PIPERAZINECARBOXYLIC ACID N-4-BOC-1-N-FMOC-2-PIPERAZINE CARBOXYLIC ACID 1-N-FMOC-4-N-BOC-PIPERAZINE-2-CARBOXYLIC ACID N-4-BOC-N-1-FMOC-2-PIPERAZINE CARBOXYLIC ACID (S)-N-1-BOC-N-4-FMOC-2-PIPERAZINE CARBOXYLIC ACID 2-PIPERAZINECARBOXYLIC ACID, N1-FMOC PROTECTED, N4-BOC PROTECTED 4-(tert-butoxycarbonyl)-1-[(9h-fluoren-9-ylmethoxy)carbonyl]- 2-piperazinecarboxylic PIPERAZINE-1,2,4-TRICARBOXYLIC ACID 4-TERT-BUTYL ESTER 1-(9H-FLUOREN-9-YLMETHYL) ESTER 4-(TERT-BUTOXYCARBONYL)-1-[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]-2-PIPERAZINECARBOXYLIC ACID 4-(tert-butoxycarbonyl)-1-[(9H-fluoren-9-ylmethoxy)carbonyl]piperazine-2-carboxylic acid (2S)-4-(tert-butoxycarbonyl)-1-[(9H-fluoren-9-ylmethoxy)carbonyl]piperazine-2-carboxylate (2R)-4-(tert-butoxycarbonyl)-1-[(9H-fluoren-9-ylmethoxy)carbonyl]piperazine-2-carboxylate 1,2,4-Piperazinetricarboxylic acid, 4-(1,1-dimethylethyl) 1-(9H-fluoren-9-ylmethyl) ester 1-(((9H-Fluoren-9-yl)Methoxy)carbonyl)-4-(tert-butoxycarbonyl)piperazine-2-carboxylic acid
CAS	183742-23-6
InChI	InChI=1/C25H28N2O6/c1-25(2,3)33-23(30)26-12-13-27(21(14-26)22(28)29)24(31)32-15-20-18-10-6-4-8-16(18)17-9-5-7-11-19(17)20/h4-11,20-21H,12-15H2,1-3H3,(H,28,29)/p-1/t21-/m1/s1

N1-FMOC-N4-BOC 2-PIPERAZINECARBOXYLIC ACID - Physico-chemical Properties

Molecular Formula	C25H28N2O6
Molar Mass	452.5
Density	1.292±0.06 g/cm3(Predicted)
Melting Point	163 °C
Boling Point	624.4±55.0 °C(Predicted)
Flash Point	331.4°C
Vapor Presure	1.88E-16mmHg at 25°C
pKa	3?+-.0.20(Predicted)
Storage Condition	2-8°C

N1-FMOC-N4-BOC 2-PIPERAZINECARBOXYLIC ACID - Risk and Safety

Risk Codes	R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S22 - Do not breathe dust. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
Hazard Note	Irritant

N1-FMOC-N4-BOC 2-PIPERAZINECARBOXYLIC ACID - Introduction

acid is an organic compound with the following properties:

1. Appearance: Common is white solid.

2. Solubility: soluble in some organic solvents, such as dimethyl thionamide (DMF) and dichloromethane (DCM).

The main use of acid is as an intermediate in organic synthesis. It can be obtained by the following preparation methods:

1. First, N-4-Boc-N-1-Fmoc-2-piperazine amine reacts with piperazine formic acid to generate piperazine formate.

2. Then, the ester is converted into the corresponding acid by hydrogenolysis reaction under acid catalysis or treatment with ammonia water.

In organic synthesis, acid is often used to introduce protecting groups (such as Boc and Fmoc) to protect sensitive functional groups to achieve specific chemical reactions.

Regarding safety information, acid is a chemical, and the following safety measures should be observed when using it:

1. Wear appropriate personal protective equipment such as lab gloves and goggles during operation.

2. Avoid contact with the skin and inhalation of its dust, such as accidental contact, should immediately rinse with plenty of water.

3 in the use of the process to avoid the fire, to avoid contact with oxidants and strong acid.

4. Storage should be sealed in a dry, cool, well-ventilated place, away from fire and acid.

Please note that the information provided here is for informational purposes only and that the specific handling and use of chemicals is subject to the relevant safety practices and laboratory safety guidelines.

Last Update：2024-04-09 21:01:54